The endometrial cancer is a cancer hormone

The causes of endometrial cancer remain unknown, but estrogens, female sex hormones play an important role. Many other risk factors have yet been identified.


 

Risk factors of endometrial cancer

The endometrial cancer affects mostly postmenopausal women, aged 60 to 70 years. This cancer is rare before age 45.

The risk of endometrial cancer are compounded when estrogens are much larger than normal (unbalanced estrogen / progesterone). For this reason this cancer is called hormone: it is activated by the hormone estrogen.

Prolonged exposure to this hormone also exhibits an over-risk. This applies, for example, women were settled early, around 12 years. But also women who are always resolved after 50 years (with a late menopause) or who have received hormone replacement therapy only estrogen. Overall, it can be a number of years of rules above average predisposition to endometrial cancer.

Also considered Risk factors for cancer of endometrial

Of irregular ovulation.

The fact of never having had children or infertility. Women without children are at risk of endometrial cancer multiplied by three.

The ovarian tumors secrete hormones.

Family history of endometrial cancer or ovarian cancer, which confer a genetic predisposition.

An endometrial hyperplasia (abnormal multiplication of cells of the endometrium).

Overweight.

Diabetes.

Disorders of the gallbladder.

Thyroid disorders.

A treatment with Tamoxifen (treatment against hormone-dependent cancers).

Note that white people are more often affected.

Each year about 5,000 new cases of endometrial cancer are diagnosed in France.